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1-14

Review Article

Status of gene therapy in 1997: molecular mechanisms, disease targets, and clinical applications.

Nikolai G. Rainov, Xandra O. Breakefield, Christof M. Kramm

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15-23

Research Article

The challenge of liposomes in gene therapy.

Kenneth Lundstrom, J. Grayson Richards, J. Richard Pink, and Francois Jenck

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25-33

Research Article

Gene transfer to the nervous system using HSV vectors.

Daniela Schober, Nora Bayer, Robert F. Murphy, Ernst Wagner and Renate Fuchs

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35-44

Review Article

The baculovirus vector system for gene delivery into hepatocytes.

Adrian Whitehouse and Alex J. Stevenson

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45-56

Review Article

Delivery systems for the MDR1 gene.

Alison A. McBride

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57-65

Review Article

Tumor killing using the HSV-tk suicide gene.

Cathryn Mah, Keyun Qing, Jonathan Hansen, Benjawan Khuntirat, Mervin C. Yoder, and Arun Srivastava

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67-74

Research Article

 Neurotrophic factor gene therapy for neurodegenerative diseases.

Torayuki Okuyama, Motomichi Kosuga, Satori Takahashi, Kyoko Sasaki, and Masao Yamada

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75-78

Minireview

Hemophilia A: current treatment and future gene therapy.

Elke Bogner

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79-89

Review Article

Gene therapy for haemophilia.

George Coukos, Stephen C. Rubin, and Katherine L Molnar-Kimber

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91-101

Review Article

Kallikrein gene therapy in hypertension, cardiovascular and renal diseases.

Mien-Chie Hung and Shao-Chun Wang

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103-112

Review Article

Chemically defined, cell-free cancer vaccines: use of tumor antigen-derived peptides or polyepitope proteins for vaccination.

John Nemunaitis

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113-121

Research Article

Somatic transgenesis by immunoglobulin genes. Gene Ther Mol Biol Vol 1, .

Dao-song Xu, Xin-yao Wu, Yun-fei Xia, Ling-hua Wu, Chao-quan Luo, Yin-hao Yang, Lu-qi Zhong, and Bin Huang

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123-131

Research Article

Applications of gene therapy in transplantation.

Bart Degrève, Erik De Clercq, Anna Karlsson, and Jan Balzarini

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133-148

Review Article

Myoblast transfer as a platform technology of gene therapy.

Giorgio Palù, Luisa Barzon, and Roberta Bonaguro

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149-155

Review Article

Constitutive activation of fibroblast growth factor receptors in human developmental syndromes.

Daniel Lee, Ken Wang, Liesl K. Nottingham, Jim Oh, David B. Weiner, and Jong J. Kim

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157-165

Review Article

 Genes involved in the control of tumor progression and their possible use for gene therapy.

Jong J. Kim, Liesl K. Nottingham, Jim Oh, Daniel Lee, Ken Wang, Mera Choi, Tzvete Dentchev, Darren Wilson, Devin M. Cunning, Ara A. Chalian, Jean Boyer, Jeong I. Sin, and David B. Weiner

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167-177

Review Article

The Apoptin gene of chicken anemia virus in the induction of apoptosis in human tumorigenic cells and in gene therapy of cancer.

Mireia Pelegrin, Danièle Noël, Mariana Marin, Estanislao Bachrach, Robert M. Saller, Brian Salmons, and Marc Piechaczyk

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179-187

Research Article

Tissue-specific triple ribozyme vectors for prostate cancer gene therapy. Gene Ther Mol Biol Vol 1,

Dolores Rodríguez, Juan Ramón Rodríguez, Mercedes Llorente, Pilar Lucas, Mariano Esteban, Carlos Martínez-A. and Gustavo del Real

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189-196

Review Article

A novel system for selection of intracellularly active ribozymes using the gene for dihydrofolate reductase (DHFR) as a selective marker in Escherichia coli.

Linda Gorman and Ryszard Kole

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197-206

Research Article

Comparison of the specificities and catalytic activities of conventional hammerhead ribozymes, Joyce's DNA enzymes, and novel dimeric minizymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA.

Jingxue Liu, Maria Filippova, Omar Fagoaga, Sandra Nehlsen-Cannarella, and Alan Escher

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207-221

Review Article

Isolation and characterization of an RNA that binds with high affinity to Tat protein of HIV-1 from a completely random pool of RNA.

DS Musgrave and Johnny Huard

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223-232

Review Article

Sequence-specific control of gene expression by antigene and clamp oligonucleotides.

Manal A. Morsy, Diane M. Harvey, and C. Thomas Caskey

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233-241

Review Article

Physical approaches to the study of chromatin fibers.

Geoffrey Goldspink, Maria Skarli and Paul Fields

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243-248

Review Article

Activation at a distance: involvement of nucleoprotein complexes that remodel chromatin.

Sherry Thornton and Raphael Hirsch

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249-256

Review Article

IDedicated sites of gene expression in the nuclei of mammalian cells. Gene Ther Mol Biol Vol 1,.

Craig H. Gelband, Michael J. Katovich, Mohan K. Raizada

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257-269

Research Article

Nuclear matrix: application to diagnosis of cancer and role in transcription and modulation of chromatin structure..

Ling Ren, Shani L. Schalles, Weihua Pan, Corinne E. Isom, Sarah E. Loy, Jia-Hai Lee, Catharine M. Benedict, Mary T. Pickering, James S. Norris, and Gary A. Clawson

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271-280

Review Article

Structural organization and biological roles of the nuclear lamina.

A. Ramezani and Sadhna Joshi

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281-291

Review Article

Analysis of mutant p53 for MAR-DNA binding: determining the dominant-oncogenic function of mutant p53.

Olubunmi Afonja, Takashi Shimamoto, John E. Smith, Jr., Long Cui, and Kenichi Takeshita

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293-300

Research Article

Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles..

Yoji Ogasawara, Yutaka Hanazono, Hiroshi Kodaira, Masashi Urabe, Hiroyuki Mano, Akira Kakizuka, Akihiro Kume, Keiya Ozawa

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301-310

Research Article

Synthetic concatemers as artificial MAR: importance of a particular configuration of short AT-tracts for protein recognition.

Peter Vanhoenacker, Walter Gommeren, Walter H.M.L. Luyten, Josée E. Leysen and Guy Haegeman

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311-325

Research Article

Replicon map of the human dystrophin gene: asymmetric replicons and putative replication barriers.

Brian E. Udashkin, Andrea Acel, Avi Shtvi, Benjamin Alt, Henry Triller, Mark A. Wainberg and Emmanuel A. Faust

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327-345

Review Article

Initiation of DNA replication at the rat aldolase B locus.—An overlapping set of DNA elements regulates transcription and replication?

Brian A. Lenzmeier and Jennifer K. Nyborg

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347-354

Review Article

TARgeting the human genome to make gene isolation easy. Gene Ther Mol Biol Vol 1,

Roxanne Y.Y. Chan and Bernard J. Jasmin

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355-371

Review Article

Control of growth and proliferation by the retinoblastoma protein..

Shen-Hsi Yang, Paula R. Yates, Yi Mo and Andrew D. Sharrocks

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373-378

  Review Article

Transcriptional regulation of the H-ras1 proto-oncogene by DNA binding proteins: mechanisms and implications in human tumorigenesis.

D.A. Spandidos, G. Sourvinos, S. Miyakis

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379-385

Review Article

Periodicity of DNA bend sites in eukaryotic genomes.

Arndt Benecke and Hinrich Gronemeyer

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387-395

Review Article

DNA methyltransferase: a downstream effector of oncogenic programs; implications for therapy.

Erik Jansen, Marleen M.R. Petit, Eric F.P.M. Schoenmakers, Torik A.Y. Ayoubi, and Wim J.M. Van de Ven

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397-412

Review Article

Correlation between DNA methylation and poly(ADP-ribosyl)ation processes.

Maria M. Krasilnikova, George M. Samadashwily and Sergei M. Mirkin

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413-422

Research Article

Poly (ADP-ribosyl)ation as one of the molecular events that accompany mammalian spermatogenesis.

Derek F.J. Ceccarelli and Lori Frappier

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423-435

Research Article

Membrane biogenesis: from mechanism to disease.

Matthias C. Huber and Constanze Bonifer

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437-445

Review Article

Cdc25 protein phosphatase: regulation and its role in cancer. Gene Ther Mol Biol Vol 1,

Ann M. Nardulli, Jongsook Kim, Jennifer R. Wood, and Lorene E. Romine

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447-453

Review Article

Nucleocytoplasmic trafficking: implications for the nuclear import of plasmid DNA during gene therapy.

Michèle Sawadogo, Xu Luo, Mario Sirito, Tao Lu, Preeti M. Ismail, Yibing Qyang, and Marilyn N. Szentirmay

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455-464

Review Article

The ATP-driven protein translocation-motor of mitochondria.

Luca Rastelli and Sadhan Majumder

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465-474

Review Article

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